Iannelli was invited by Frank Lloyd Wright to work on the Midway Gardens project, when Iannelli created several of the Midway's "Sprite" sculptures. Wright, as he often did, took credit for the statues, thus ending any collaborations with Wright.
When Enrst Grunfeld designed the Adler Planitarium in the late 1920s, Ianelli designed and created the famous art deco plaques of zodiac signs and of the planets. The plaques were created before the discovery of Pluto, so the little planet was missing from the Solar System display. Now that Pluto has been demoted and is no longer considered a planet, Ianelli's work is correct again!
He went on to open Iannelli Studios in Park Ridge, Illinois.
Alphonso Ianelli died on March 23, 1965 in Chicago.